The 2-Minute Rule for cees dekker
The 2-Minute Rule for cees dekker
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Utilizing single-molecule optical and AFM imaging and pressure-spectroscopy tactics, we seek out to unravel the mechanistic aspects of the composition and dynamics of chromosomes. Our investigation passions include:
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‘It had been merely a matter of buying up a e book on cell biology and beginning to examine. I had come from a environment of ultra-higher vacuums, cryostats and quantum phenomena, and now I had been working at place temperature with molecular biology kits.
Sculpting nano-electrodes with a transmission electron beam for electrical and geometrical characterization of nanoparticles.
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Case in point (3) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is revealed in gray, the rim from the pore is highlighted in pink, plus a 3D rendering from the movement on the DNA rod is displayed.
Length Charge of unique carbon nanotubes by nanostructuring While using the scanning tunneling microscope
Researching DNA loop extrusion by SMC proteins for chromosome architecture with solitary-molecule assays.
Knowing basic processes regulating the spatial and dynamic organisation in the DNA in Dwell cells.
‘The fantastically delicate way through which factors in nature functionality hardly ever ceases to amaze me. If we clear up the puzzle of how daily life came into remaining, I be expecting that my amazement with the complexity of creation will have amplified and with it my awe to the greatness in the Creator.’
FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division
1999, initial measurement of your wavefunction of single molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive proof for a new Luttinger description of interacting electrons in nanotubes
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2004, discovery of new physics in translocation of DNA by nanopores; initial experimental analyze of ions conduction in nanofluidic channels; very first electrochemistry with individual solitary-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; very first electrical docking of microtubules on kinesin-coated nanostructures; to start with biophysics characterization in the mechanical properties of double-stranded RNA; and 1st ceesdekker one-molecule examine of DNA translocation by a restriction-modification enzyme.